Neil Carragher: search on Z-Library

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1

eCF309 : a potent, selective and cell-permeable mTOR inhibitor

Fraser, Craig, Carragher, Neil O., Unciti-Broceta, Asier

Journal:

Year:

2016

Language:

english

File:

PDF, 2.25 MB

english, 2016

2

Accelerating glioblastoma drug discovery: Convergence of patient-derived models, genome editing and phenotypic screening

O'Duibhir, Eoghan, Carragher, Neil, Pollard, Steven M.

Journal:

Molecular and Cellular Neuroscience

Year:

2016

Language:

english

File:

PDF, 1.10 MB

english, 2016

3

Preclinical anticancer activity of the potent, oral Src inhibitor AZD0530

Tim P. Green, Mike Fennell, Robin Whittaker, Jon Curwen, Vivien Jacobs, Jack Allen, Armelle Logie, Judith Hargreaves, D. Mark Hickinson, Robert W. Wilkinson, Paul Elvin, Brigitte Boyer, Neil Carragher

Journal:

Molecular Oncology

Year:

2009

Language:

english

File:

PDF, 808 KB

english, 2009

4

Machine Learning Enables Live Label-Free Phenotypic Screening in Three Dimensions

O'Duibhir, Eoghan, Paris, Jasmin, Lawson, Hannah, Sepulveda, Catarina, Shenton, Dahlia Doughty, Carragher, Neil O., Kranc, Kamil R.

Journal:

Assay and Drug Development Technologies

Year:

2018

Language:

english

File:

PDF, 2.47 MB

english, 2018

5

Calpain: a role in cell transformation and migration

Neil O Carragher, Margaret C Frame

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2002

Language:

english

File:

PDF, 267 KB

english, 2002

6

Correction: eCF309 : a potent, selective and cell-permeable mTOR inhibitor

Fraser, Craig, Carragher, Neil O., Unciti-Broceta, Asier

Journal:

Year:

2016

Language:

english

File:

PDF, 113 KB

english, 2016

7

Real Time Detection of In Vitro Tumor Cell Apoptosis Induced by CD8+ T Cells to Study Immune Suppressive Functions of Tumor-infiltrating Myeloid Cells

Kitamura, Takanori, Doughty-Shenton, Dahlia, Pollard, Jeffrey W., Carragher, Neil O.

Journal:

Journal of Visualized Experiments

Year:

2019

File:

PDF, 2.49 MB

2019

8

Profiling distinct mechanisms of tumour invasion for drug discovery: imaging adhesion, signalling and matrix turnover

Neil O. Carragher

Journal:

Clinical and Experimental Metastasis

Year:

2009

Language:

english

File:

PDF, 651 KB

english, 2009

9

Ret inhibition decreases growth and metastatic potential of estrogen receptor positive breast cancer cells

Gattelli, Albana, Nalvarte, Ivan, Boulay, Anne, Roloff, Tim C., Schreiber, Martin, Carragher, Neil, Macleod, Kenneth K., Schlederer, Michaela, Lienhard, Susanne, Kenner, Lukas, Torres-Arzayus, Maria I

Journal:

EMBO Molecular Medicine

Year:

2013

Language:

english

File:

PDF, 1.40 MB

english, 2013

10

The role of focal-adhesion kinase in cancer — a new therapeutic opportunity

McLean, Gordon W., Carragher, Neil O., Avizienyte, Egle, Evans, Jeff, Brunton, Valerie G., Frame, Margaret C.

Journal:

Nature Reviews Cancer

Year:

2005

Language:

english

File:

PDF, 494 KB

english, 2005

11

Focal adhesion and actin dynamics: a place where kinases and proteases meet to promote invasion

Neil O. Carragher, Margaret C. Frame

Journal:

Trends in Cell Biology

Year:

2004

Language:

english

File:

PDF, 438 KB

english, 2004

12

Role of Discoidin Domain Receptors 1 and 2 in Human Smooth Muscle Cell-Mediated Collagen Remodeling: Potential Implications in Atherosclerosis and Lymphangioleiomyomatosis

Nicola Ferri, Neil O. Carragher, Elaine W. Raines

Journal:

The American Journal of Pathology

Year:

2004

Language:

english

File:

PDF, 874 KB

english, 2004

13

N-alkynyl derivatives of 5-fluorouracil: susceptibility to palladium-mediated dealkylation and toxigenicity in cancer cell culture

Weiss, Jason T., Fraser, Craig, Rubio-Ruiz, BelÃ©n, Myers, Samuel H., Crispin, Richard, Dawson, John C., Brunton, Valerie G., Patton, E. Elizabeth, Carragher, Neil O., Unciti-Broceta, Asier

Journal:

Frontiers in Chemistry

Year:

2014

Language:

english

File:

PDF, 2.88 MB

english, 2014

14

Developments in preclinical cancer imaging: innovating the discovery of therapeutics

Conway, James R. W., Carragher, Neil O., Timpson, Paul

Journal:

Nature Reviews Cancer

Year:

2014

Language:

english

File:

PDF, 4.73 MB

english, 2014

15

Targeting of Slc25a21 Is Associated with Orofacial Defects and Otitis Media Due to Disrupted Expression of a Neighbouring Gene

Maguire, Simon, Estabel, Jeanne, Ingham, Neil, Pearson, Selina, Ryder, Edward, Carragher, Damian M., Walker, Nicolas, Bussell, James, Chan, Wai-In, Keane, Thomas M., Adams, David J., Scudamore, Cheryl

Journal:

Year:

2014

Language:

english

File:

PDF, 2.21 MB

english, 2014

16

Novel roles of PRK1 and PRK2 in cilia and cancer biology

Patel, Hitesh, Li, Jun, Herrero, Ana, Kroboth, Jakob, Byron, Adam, Kriegsheim, Alex Von, Brunton, Valerie, Carragher, Neil, Hurd, Toby, Frame, Margaret

Journal:

Scientific Reports

Year:

2020

File:

PDF, 3.27 MB

2020

17

The mechanism of cell cycle regulation by v-Src

Riley, Deborah, Carragher, Neil O, Frame, Margaret C, Wyke, John A

Journal:

Year:

2001

Language:

english

File:

PDF, 346 KB

english, 2001

18

Correlation of plasma IGF-I concentrations and growth rate in aquacultured finfish: a tool for assessing the potential of new diets

Anthony R Dyer, Christopher G Barlow, Matthew P Bransden, Chris G Carter, Brett D Glencross, Neil Richardson, Philip M Thomas, Kevin C Williams, John F Carragher

Journal:

Year:

2004

Language:

english

File:

PDF, 205 KB

english, 2004

19

Concerns, challenges and promises of high-content analysis of 3D cellular models

Carragher, Neil, Piccinini, Filippo, Tesei, Anna, Jr, O. Joseph Trask, Bickle, Marc, Horvath, Peter

Journal:

Nature Reviews Drug Discovery

Year:

2018

Language:

english

File:

PDF, 137 KB

english, 2018

20

Development and Bioorthogonal Activation of Palladium-Labile Prodrugs of Gemcitabine

Weiss, Jason T., Dawson, John C., Fraser, Craig, Rybski, Witold, Torres-Sánchez, Carmen, Bradley, Mark, Patton, E. Elizabeth, Carragher, Neil O., Unciti-Broceta, Asier

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 4.67 MB

english, 2014

21

Pharmaco-genomic investigations of organo-iridium anticancer complexes reveal novel mechanism of action

Hearn, Jessica M., Hughes, George M., Romero-Canelón, Isolda, Munro, Alison F., Rubio-Ruiz, Belén, Liu, Zhe, Carragher, Neil O., Sadler, Peter J.

Journal:

Year:

2017

Language:

english

File:

PDF, 5.23 MB

english, 2017

22

Engineered Mutations Change the Structure and Stability of a Virus-Like Particle

Fiedler, Jason D., Higginson, Cody, Hovlid, Marisa L., Kislukhin, Alexander A., Castillejos, Alexandra, Manzenrieder, Florian, Campbell, Melody G., Voss, Neil R., Potter, Clinton S., Carragher, Bridge

Journal:

Biomacromolecules

Year:

2012

Language:

english

File:

PDF, 1.89 MB

english, 2012

23

Combining imaging and pathway profiling: an alternative approach to cancer drug discovery

Neil O. Carragher, Valerie G. Brunton, Margaret C. Frame

Journal:

Drug Discovery Today

Year:

2012

Language:

english

File:

PDF, 1.66 MB

english, 2012

24

The oncogene Gankyrin is expressed in testicular cancer and contributes to cisplatin sensitivity in embryonal carcinoma cells

Camacho-Moll, Maria E., Macdonald, Joni, Looijenga, L. H. J., Rimmer, Michael P., Donat, Roland, Marwick, John A., Shukla, C. J., Carragher, Neil, Jørgensen, Anne, Mitchell, Rod T.

Journal:

Year:

2019

Language:

english

File:

PDF, 9.02 MB

english, 2019

25

A Synergistic Anticancer FAK and HDAC Inhibitor Combination Discovered by a Novel ChemicalâGenetic High-Content Phenotypic Screen

Dawson, John C., Serrels, Bryan, Byron, Adam, Muir, Morwenna T., Makda, Ashraff, GarcÃa-MuÃ±oz, Amaya, von Kriegsheim, Alex, Lietha, Daniel, Carragher, Neil O., Frame, Margaret C.

Journal:

Molecular Cancer Therapeutics

Year:

2020

Language:

english

File:

PDF, 2.39 MB

english, 2020

26

Combined targeting of MEK and the glucocorticoid receptor for the treatment of RAS-mutant multiple myeloma

Sriskandarajah, Priya, De Haven Brandon, Alexis, MacLeod, Kenneth, Carragher, Neil O., Kirkin, Vladimir, Kaiser, Martin, Whittaker, Steven R.

Journal:

Year:

2020

File:

PDF, 2.96 MB

2020

27

V-SRC'S HOLD OVER ACTIN AND CELL ADHESIONS

Frame, Margaret C., Fincham, Valerie J., Carragher, Neil O., Wyke, John A.

Journal:

Nature Reviews Molecular Cell Biology

Year:

2002

Language:

english

File:

PDF, 3.40 MB

english, 2002

28

The PI3K Pathway Balances Self-Renewal and Differentiation of Nephron Progenitor Cells through β-Catenin Signaling

Lindström, Nils Olof, Carragher, Neil Oliver, Hohenstein, Peter

Journal:

Stem Cell Reports

Year:

2015

Language:

english

File:

PDF, 4.67 MB

english, 2015

29

Naturally Inspired Peptide Leads: Alanine Scanning Reveals an Actin-Targeting Thiazole Analogue of Bisebromoamide

Johnston, Heather J, Boys, Sarah K, Makda, Ashraff, Carragher, Neil O, Hulme, Alison Nicola

Journal:

Year:

2016

Language:

english

File:

PDF, 1.03 MB

english, 2016

30

Empirical drug discovery: a view from the proteome

Lee, Jonathan A., Carragher, Neil O., Berg, Ellen L.

Journal:

Drug Discovery Today: Technologies

Year:

2017

Language:

english

File:

PDF, 711 KB

english, 2017

31

Monocytes Differentiate to Immune Suppressive Precursors of Metastasis-Associated Macrophages in Mouse Models of Metastatic Breast Cancer

Kitamura, Takanori, Doughty-Shenton, Dahlia, Cassetta, Luca, Fragkogianni, Stamatina, Brownlie, Demi, Kato, Yu, Carragher, Neil, Pollard, Jeffrey W.

Journal:

Frontiers in Immunology

Year:

2018

Language:

english

File:

PDF, 5.01 MB

english, 2018

32

High-Content Phenotypic Profiling in Esophageal Adenocarcinoma Identifies Selectively Active Pharmacological Classes of Drugs for Repurposing and Chemical Starting Points for Novel Drug Discovery

Hughes, Rebecca E., Elliott, Richard J. R., Munro, Alison F., Makda, Ashraff, OâNeill, J. Robert, Hupp, Ted, Carragher, Neil O.

Journal:

Year:

2020

File:

PDF, 3.95 MB

2020

33

ADF and Cofilin1 Control Actin Stress Fibers, Nuclear Integrity, and Cell Survival

Kanellos, Georgios, Zhou, Jing, Patel, Hitesh, Ridgway, Rachel A., Huels, David, Gurniak, Christine B., Sandilands, Emma, Carragher, Neil O., Sansom, Owen J., Witke, Walter, Brunton, Valerie G., Frame

Journal:

Year:

2015

Language:

english

File:

PDF, 6.55 MB

english, 2015

34

Palladium-Mediated Dealkylation of N-Propargyl-Floxuridine as a Bioorthogonal Oxygen-Independent Prodrug Strategy

Weiss, Jason T., Carragher, Neil O., Unciti-Broceta, Asier

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 831 KB

english, 2015

35

Blocking distinct interactions between Glioblastoma cells and their tissue microenvironment: A novel multi-targeted therapeutic approach

Mettang, Melanie, Meyer-Pannwitt, Viola, Karpel-Massler, Georg, Zhou, Shaoxia, Carragher, Neil O., Föhr, Karl Josef, Baumann, Bernd, Nonnenmacher, Lisa, Enzenmüller, Stefanie, Dahlhaus, Meike, Siegeli

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 5.60 MB

english, 2018

36

The retinal tyrosine kinome of diabetic Akimba mice highlights potential for specific SRC family kinase inhibition in retinal vascular disease

Sergeys, Jurgen, Van Hove, Inge, Hu, Tjing-Tjing, Temps, Carolin, Carragher, Neil O., Unciti-Broceta, Asier, Feyen, Jean H.M., Moons, Lieve, Porcu, Michael

Journal:

Experimental Eye Research

Year:

2020

File:

PDF, 5.67 MB

2020

37

A Novel Role for FAK as a Protease-Targeting Adaptor Protein: Regulation by p42 ERK and Src

Neil O. Carragher, M.Andrew Westhoff, Valerie J. Fincham, Michael D. Schaller, Margaret C. Frame

Journal:

Current Biology

Year:

2003

Language:

english

File:

PDF, 522 KB

english, 2003

38

A test-bed for optimizing high-resolution single particle reconstructions

Scott M. Stagg, Gabriel C. Lander, Joel Quispe, Neil R. Voss, Anchi Cheng, Henry Bradlow, Steven Bradlow, Bridget Carragher, Clinton S. Potter

Journal:

Journal of Structural Biology

Year:

2008

Language:

english

File:

PDF, 2.85 MB

english, 2008

39

Development of the Theta Comparative Cell Scoring Method to Quantify Diverse Phenotypic Responses Between Distinct Cell Types

Warchal, Scott J., Dawson, John C., Carragher, Neil O.

Journal:

Assay and Drug Development Technologies

Year:

2016

Language:

english

File:

PDF, 1.11 MB

english, 2016

40

Modelling distinct modes of tumour invasion and metastasis

Neil O. Carragher, Margaret C. Frame

Journal:

Drug Discovery Today: Disease Models

Year:

2011

Language:

english

File:

PDF, 1.32 MB

english, 2011

41

Extracellular palladium-catalysed dealkylation of 5-fluoro-1-propargyl-uracil as a bioorthogonally activated prodrug approach

Weiss, Jason T., Dawson, John C., Macleod, Kenneth G., Rybski, Witold, Fraser, Craig, Torres-Sánchez, Carmen, Patton, E. Elizabeth, Bradley, Mark, Carragher, Neil O., Unciti-Broceta, Asier

Journal:

Nature Communications

Year:

2014

Language:

english

File:

PDF, 2.04 MB

english, 2014

42

Advanced intravital subcellular imaging reveals vital three-dimensional signalling events driving cancer cell behaviour and drug responses in live tissue

Nobis, Max, Carragher, Neil O., McGhee, Ewan J., Morton, Jennifer P., Sansom, Owen J., Anderson, Kurt I., Timpson, Paul

Journal:

Year:

2013

Language:

english

File:

PDF, 779 KB

english, 2013

43

Next-generation phenotypic screening

Warchal, Scott J, Unciti-Broceta, Asier, Carragher, Neil O

Journal:

Future Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.20 MB

english, 2016

44

Live Cell in Vitro and in Vivo Imaging Applications: Accelerating Drug Discovery

Isherwood, Beverley, Timpson, Paul, McGhee, Ewan J, Anderson, Kurt I, Canel, Marta, Serrels, Alan, Brunton, Valerie G, Carragher, Neil O

Journal:

Year:

2011

Language:

english

File:

PDF, 2.04 MB

english, 2011

45

Advancing cancer drug discovery towards more agile development of targeted combination therapies

Carragher, Neil O, Unciti-Broceta, Asier, Cameron, David A

Journal:

Future Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 4.12 MB

english, 2012

46

Inside Cover: Naturally Inspired Peptide Leads: Alanine Scanning Reveals an Actin-Targeting Thiazole Analogue of Bisebromoamide (ChemBioChem 17/2016)

Johnston, Heather J., Boys, Sarah K., Makda, Ashraff, Carragher, Neil O., Hulme, Alison N.

Journal:

Year:

2016

File:

PDF, 3.53 MB

2016

47

High Content Phenotypic Screening Identifies Serotonin Receptor Modulators with Selective Activity upon Breast Cancer Cell Cycle and Cytokine Signaling Pathways

Warchal, Scott J., Dawson, John C., Shepherd, Emelie, Munro, Alison F., Hughes Ashraff Makda, Rebecca E., Carragher, Neil O.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2019

File:

PDF, 3.02 MB

2019

48

Mammary Tumor Cells with High Metastatic Potential Are Hypersensitive to Macrophage-Derived HGF

Kitamura, Takanori, Kato, Yu, Brownlie, Demi, Soong, Daniel Y.H., Sugano, Gaël, Kippen, Nicolle, Li, Jiufeng, Doughty-Shenton, Dahlia, Carragher, Neil, Pollard, Jeffrey W.

Journal:

Cancer Immunology Research

Year:

2019

File:

PDF, 1.79 MB

2019

49

Potent organo-osmium compound shifts metabolism in epithelial ovarian cancer cells

Hearn, Jessica M., Romero-Canelón, Isolda, Munro, Alison F., Fu, Ying, Pizarro, Ana M., Garnett, Mathew J., McDermott, Ultan, Carragher, Neil O., Sadler, Peter J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.00 MB

english, 2015

50

Mammary Tumor Cells with High Metastatic Potential Are Hypersensitive to Macrophage-Derived HGF

Kitamura, Takanori, Kato, Yu, Brownlie, Demi, Soong, Daniel Y.H., Sugano, Gaël, Kippen, Nicolle, Li, Jiufeng, Doughty-Shenton, Dahlia, Carragher, Neil, Pollard, Jeffrey W.

Journal:

Cancer Immunology Research

Year:

2019

Language:

english

File:

PDF, 1.79 MB

english, 2019

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